Know When to Consider Using Topical or Nebulized Tranexamic Acid

You'll see tranexamic acid used topically or via nebulizer...in addition to typical routes, such as IV in trauma or postpartum hemorrhage.

Topical tranexamic acid is gaining traction for epistaxis.

Inserting a cotton pledget soaked in injectable tranexamic acid seems to decrease bleeding time by about 5 minutes and increase ED discharges at 2 hours compared to topical epinephrine and lidocaine...even in patients taking antiplatelets.