how to handle drug interaction alerts for tramadol

March 2012

Questions often come up about how to handle drug interaction alerts for tramadol.

These alerts are common because tramadol acts like a weak opioid...AND it inhibits the reuptake of serotonin and norepinephrine.

Decide if the alert is clinically important based on the patient's other meds and medical history.

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Table of Contents

Cardiology new Chest guidelines will create more debate about which anticoagulant to use to prevent strokes in atrial fib patients
Cardiology more generic ARBs in 2012
Gastroenterology new warnings that PPIs (omeprazole, etc) might increase the risk of Clostridium difficile-associated diarrhea
Women's Health whether it's okay for women with migraine headaches to use combined oral contraceptives
Diabetes Bydureon (by-DUR-ee-on), the new long-acting form of Byetta (exenatide) for type 2 diabetes
Dermatology Picato (pih-KAY-toe) gel as a more convenient topical treatment for actinic keratosis
Dermatology Many OTCs for bruises and scars don't work
Infectious Diseases fewer options for treating pinworms now that mebendazole (Vermox, etc) is discontinued
Antithrombotics whether it's okay to use aspirin to prevent thrombosis after hip or knee replacement surgery
Opioids how to handle drug interaction alerts for tramadol
Practice if their meds contain animal products
Neurology & Pain You'll get questions about what works for essential tremor